Quetiapine Shows Promising Results for Treatment of Generalized ...

...ba href=/anxiety/a/b news E-Mail this DGDispatch to a colleague DGDispatch Quetiapine Shows Promising Results for Treatment of Generalized ba href=/anxiety/a/b Disorder: Presented at ADAA MIAMI, F.L.

- March 27, 2006 - Two studies presented here at the 26th annual conference of the ba href=/anxiety/a/b Disorders Association of America (ADAA) show promising results for use of the atypical antipsychotic, quetiapine, as both monotherapy and adjunctive therapy for treatment of generalized ba href=/anxiety/a/b disorder (GAD).

One study was presented on March 25th by lead investigator Olga Brawman-Mintzer, associate professor, Department of Psychiatry, Medical University of South Carolina, Charleston, South Carolina, United States.

Dr.

Brawman-Mintzer and colleagues tested quetiapine in 38 non-depressed patients with GAD, who had a mean total Hamilton Rating Scale for ba href=/anxiety/a/b (HAM-A) score of 20 or greater.

After a 1-week placebo run-in period, 19 subjects were randomized to 6 weeks of double-blind treatment with quetiapine 25-300 mg/day and 19 received placebo.

Quetiapine dosing was escalated to a maximum daily dose of 300 mg/day over a 2-week period based on tolerability and clinical response.

Patients were assessed at baseline and weeks 1, 2, 4 and 6.

The mean dose of quetiapine at the trial end was 125 mg/day.

Completion rates were 63.2% in the quetiapine group and 84.2% in the placebo group.

Five patients in the quetiapine group and 2 in the placebo group discontinued treatment because of adverse events.

One patient in ea...

Crude Oil Futures Ease; Prices See Uptick

...ba href=/anxiety/a/b about the next hurricane season in the Gulf of Mexico, were expected to limit the price decline.

Some analysts believe gasoline prices could climb as high as $3 a gallon this summer, though that assumes some significant disruptions at refineries, or difficulty in getting fuel to markets.On Monday, militants in Nigeria's oil-rich southern delta released their last remaining foreign hostages _ two Americans and one Briton _ more than five weeks after the oil-industry workers were kidnapped.The militants took nine foreign oil workers hostage Feb.

18 from a barge owned by Houston-based oil services company Willbros Group Inc., which was laying pipeline in the delta for Royal Dutch Shell PLC.

The group released six of the captives after 12 days in captivity.The militants are behind a spate of attacks that have cut Nigeria's oil exports by more than 20 percent.

On Saturday, they said they killed three soldiers in fresh clashes near a key natural gas plant run by Shell.

Shell said there was no impact on the gas plant.Iran, the No.

2 oil producer in OPEC, also remains a potential source of concern.

It has been referred to the U.N.

Security Council over fears it may want to misuse its nuclear program to make weapons, but the council has been at loggerheads over U.S.-led efforts to ratchet up the pressure on Tehran.In other Nymex trading, natural gas futures fell 22.3 cents to settle at $7.067 per 1,000 cubic feet.

Heating oil futures fell 1.13 cent to close at $1.7811 a gallon...

Crude oil futures slip, but hold above US$64 a barrel

...ba href=/anxiety/a/b about the next hurricane season in the Gulf of Mexico, were expected to limit the price decline.

Some analysts believe gasoline prices could climb as high as $3 a gallon this summer, though that assumes some significant disruptions at refineries, or difficulty in getting fuel to markets.

On Monday, militants in Nigeria's oil-rich southern delta released their last remaining foreign hostages - two Americans and one Briton - more than five weeks after the oil-industry workers were kidnapped.

The militants took nine foreign oil workers hostage Feb.

18 from a barge owned by Houston-based oil services company Willbros Group Inc., which was laying pipeline in the delta for Royal Dutch Shell PLC.

The group released six of the captives after 12 days in captivity.

The militants are behind a spate of attacks that have cut Nigeria's oil exports by more than 20 per cent.

On Saturday, they said they killed three soldiers in fresh clashes near a key natural gas plant run by Shell.

Shell said there was no impact on the gas plant.

Iran, the No.

2 oil producer in OPEC, also remains a potential source of concern.

It has been referred to the U.N.

Security Council over fears it may want to misuse its nuclear program to make weapons, but the council has been at loggerheads over U.S.-led efforts to ratchet up the pressure on the Iranian government.

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